Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6.,Blood Cancer Journal

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Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6.
Blood Cancer Journal ( IF 12.9 ) Pub Date : 2022-04-13 , DOI: 10.1038/s41408-022-00658-w
Alyssa Clay-Gilmour ₁ , Subhayan Chattopadhyay ₂ , Michelle A T Hildebrandt ₃ , Hauke Thomsen _{4,

5} , Niels Weinhold ₆ , Pavel Vodicka _{7,

8,

9} , Ludmila Vodickova _{7,

8,

9} , Per Hoffmann _{10,

11} , Markus M Nöthen ₁₀ , Karl-Heinz Jöckel ₁₂ , Börge Schmidt ₁₂ , Christian Langer ₁₃ , Roman Hajek ₁₄ , Göran Hallmans ₁₅ , Ulrika Pettersson-Kymmer ₁₆ , Claes Ohlsson ₁₇ , Florentin Späth ₁₈ , Richard Houlston ₁₉ , Hartmut Goldschmidt _{6,

20} , Elisabet E Manasanch ₃ , Aaron Norman ₂₁ , Shaji Kumar ₂₂ , S Vincent Rajkumar ₂₂ , Susan Slager _{21,

22} , Asta Försti _{23,

24} , Celine M Vachon ₂₅ , Kari Hemminki _{26,

27}

Affiliation

Arnold School of Public Health, Department of Epidemiology & Biostatistics, University of South Carolina, Columbia, SC, USA.
Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.
Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
GeneWerk GmbH, Im Neuenheimer Feld 582, 6910, Heidelberg, Germany.
Center for Primary Health Care Research, Lund University, Malmo, Sweden.
Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.
Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00, Prague, Czech Republic.
Institute of Biology and Medical Genetics, 1st Medical Faculty, Charles University, Albertov 4, 128 00, Prague, Czech Republic.
Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, 30605, Pilsen, Czech Republic.
Institute of Human Genetics, University of Bonn, Bonn, Germany.
Department of Biomedicine, University of Basel, Basel, Switzerland.
Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany.
Department of Internal Medicine III, University of Ulm, Ulm, Germany.
Department of Hematooncology, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic.
Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden.
Clinical Pharmacology, Department of Integrative Medical Biology, Umea University, Umea, Sweden.
Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden.
Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
National Centre of Tumor Diseases, Heidelberg, Germany.
Division of Computational Genomics, Mayo Clinic, Rochester, MN, USA.
Division of Hematology, Mayo Clinic Rochester Mayo Clinic, Rochester, MN, USA.
Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.
Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Biomedical Center, Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, 30605, Pilsen, Czech Republic.
Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120, Heidelberg, Germany.