On 11 March 2020, the WHO declared the coronavirus disease 2019 (COVID-19) outbreak a pandemic and COVID-19 emerged as one of the biggest challenges in public health and economy in the twenty-first century. The respiratory tract has been the centre of attention, but COVID-19-associated complications affecting the genitourinary tract are reported frequently, raising concerns about possible long-term damage in these organs. The angiotensin-converting enzyme 2 (ACE2) receptor, which has a central role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invasion, is highly expressed in the genitourinary tract, indicating that these organs could be at a high risk of cell damage. The detection of SARS-CoV-2 in urine and semen is very rare; however, COVID-19 can manifest through urological symptoms and complications, including acute kidney injury (AKI), which is associated with poor survival, severe structural changes in testes and impairment of spermatogenesis, and hormonal imbalances (mostly secondary hypogonadism). The effect of altered total testosterone levels or androgen deprivation therapy on survival of patients with COVID-19 was intensively debated at the beginning of the pandemic; however, androgen inhibition did not show any effect in preventing or treating COVID-19 in a clinical study. Thus, urologists have a crucial role in detecting and managing damage of the genitourinary tract caused by COVID-19.

2020 年 3 月 11 日，世界卫生组织宣布 2019 年冠状病毒病 (COVID-19) 爆发为大流行病，COVID-19 成为二十一世纪公共卫生和经济面临的最大挑战之一。呼吸道一直是关注的焦点，但影响泌尿生殖道的 COVID-19 相关并发症的报道频繁，引发了人们对这些器官可能遭受长期损害的担忧。血管紧张素转换酶 2 (ACE2) 受体在严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 入侵中起着核心作用，在泌尿生殖道中高度表达，表明这些器官可能处于高危状态的细胞损伤。在尿液和精液中检测到 SARS-CoV-2 非常罕见；然而，COVID-19 可以通过泌尿系统症状和并发症表现出来，包括急性肾损伤 (AKI)，它与生存率低下、睾丸结构严重改变和精子发生受损以及荷尔蒙失调（主要是继发性性腺功能减退症）有关。总睾酮水平改变或雄激素剥夺疗法对 COVID-19 患者生存的影响在大流行开始时引起了激烈争论；然而，在临床研究中，抑制雄激素对预防或治疗 COVID-19 没有任何作用。因此，泌尿科医生在检测和管理由 COVID-19 引起的泌尿生殖道损伤方面起着至关重要的作用。总睾酮水平改变或雄激素剥夺疗法对 COVID-19 患者生存的影响在大流行开始时引起了激烈争论；然而，在临床研究中，抑制雄激素对预防或治疗 COVID-19 没有任何作用。因此，泌尿科医生在检测和管理由 COVID-19 引起的泌尿生殖道损伤方面起着至关重要的作用。总睾酮水平改变或雄激素剥夺疗法对 COVID-19 患者生存的影响在大流行开始时引起了激烈争论；然而，在临床研究中，抑制雄激素对预防或治疗 COVID-19 没有任何作用。因此，泌尿科医生在检测和管理由 COVID-19 引起的泌尿生殖道损伤方面起着至关重要的作用。