Lv, Liu, Mo and colleagues demonstrate that in pancreatic ductal adenocarcinoma cells, gasdermin E transports the transcription factor YBX1 to the nucleus, where it promotes the expression of mucins, thereby providing tumour cells with a barrier against digestive enzymes.

中文翻译：

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Gasdermin E 屏蔽 PDAC

Lv、Liu、Mo 及其同事证明，在胰腺导管腺癌细胞中，gasdermin E 将转录因子 YBX1 转运到细胞核，在那里它促进粘蛋白的表达，从而为肿瘤细胞提供了对抗消化酶的屏障。