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Racial Disparities in Associations of Alcohol Consumption With Liver Disease Mortality in a Predominantly Low-Income Population: A Report From the Southern Community Cohort Study.
The American Journal of Gastroenterology ( IF 8.0 ) Pub Date : 2022-04-13 , DOI: 10.14309/ajg.0000000000001768
Lei Fan 1 , Xiangzhu Zhu 1 , Alexandra Shingina 2 , Edmond K Kabagambe 3 , Martha J Shrubsole 1 , Qi Dai 1
Affiliation  

Consistent with previous cross-sectional studies, in the Southern Community Cohort Study, the largest cohort for Black Americans conducted in a predominantly low-income population with 81,694 participants, we found that moderate alcohol drinking was associated with a significantly increased risk of mortality due to liver disease in Black Americans (hazard ratio = 2.06; 95% confidence interval: 1.08-3.94) but not in White Americans (hazard ratio = 0.87; 95% confidence interval: 0.52-1.44). We found that heavy drinking was significantly associated with an increased risk of mortality due to liver disease in both Black and White Americans. Future studies are warranted to understand the mechanism involving such racial disparity.

中文翻译:

主要是低收入人群中饮酒与肝病死亡率之间的种族差异:来自南方社区队列研究的报告。

与之前的横断面研究一致,在南方社区队列研究(主要是低收入人群中进行的最大的美国黑人队列研究,共有 81,694 名参与者)中,我们发现适度饮酒与死亡风险显着增加相关,这是由于美国黑人患有肝病(风险比 = 2.06;95% 置信区间:1.08-3.94),但美国白人则没有(风险比 = 0.87;95% 置信区间:0.52-1.44)。我们发现,在美国黑人和白人中,大量饮酒与肝病死亡风险增加显着相关。未来的研究有必要了解涉及这种种族差异的机制。
更新日期:2022-04-13
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