In adolescence, both major depression (MD) and anorexia nervosa (AN) are associated with deficits in emotion regulation (ER). However, studies have yet to compare ER profiles within the disorders and the effect of comorbid MD+AN is unclear. This study examined the habitual use of ER in 229 girls, aged 12–18 years, with MD (n = 84), AN (n = 37), comorbid MD+AN (n = 25), and healthy girls (n = 83). Girls with MD, AN and MD+AN reported more maladaptive and less adaptive ER strategies than healthy girls. MD and MD+AN groups showed more frequent use of maladaptive ER compared to only AN, with no differences between only MD and MD+AN. This suggests that MD+AN is not necessarily associated with higher ER deficits, rather, an additional diagnosis of MD exacerbates impairments in AN. Identifying specific ER profiles can provide important targets in prevention and treatment for AN, MD and AN+MD.

在青春期，重度抑郁症 (MD) 和神经性厌食症 (AN) 都与情绪调节 (ER) 缺陷有关。然而，研究尚未比较疾病中的 ER 谱，并且共病 MD+AN 的影响尚不清楚。本研究检查了 229 名 12-18 岁女孩习惯性使用 ER，患有 MD (n = 84)、AN (n = 37)、共病 MD+AN (n = 25) 和健康女孩 (n = 83) ）。与健康女孩相比，患有 MD、AN 和 MD+AN 的女孩报告的 ER 策略适应不良和适应性较差。与仅使用 AN 相比，MD 和 MD+AN 组更频繁地使用适应不良的 ER，仅 MD 和 MD+AN 之间没有差异。这表明 MD + AN 不一定与更高的 ER 缺陷相关，相反，对 MD 的额外诊断会加剧 AN 的损伤。