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DC1s shield Tpex cells to bolster PD-1 blockade
Immunity ( IF 25.5 ) Pub Date : 2022-04-12 , DOI: 10.1016/j.immuni.2022.03.017
David G Brooks 1 , Pamela S Ohashi 1
Affiliation  

Responsiveness to PD-1 blockade depends on a cell subset known as Tpex cells, but how these cells are sustained is less understood. In this issue of Immunity, Dähling et al. show how dendritic cells form a niche for Tpex preservation.



中文翻译:

DC1s 屏蔽 Tpex 细胞以加强 PD-1 阻断

对 PD-1 阻断剂的反应取决于称为 Tpex 细胞的细胞亚群,但人们对这些细胞的维持方式知之甚少。在本期Immunity中,Dähling 等人。显示树突细胞如何形成 Tpex 保存的利基。

更新日期:2022-04-12
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