Target-of-rapamycin complex 1 resides on lysosomes/vacuoles and additionally on signaling endosomes. Gao et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202109084) set out to define the molecular identity of signaling endosomes, along with players required for the formation and maintenance of this endosomal subpopulation.

中文翻译：

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建立对 TORC1 信号传导的空间控制

雷帕霉素复合物 1 的靶标驻留在溶酶体/液泡上，此外还驻留在信号内体上。高等人。(2022. J. Cell Biol.https://doi.org/10.1083/jcb.202109084) 着手定义信号内体的分子身份，以及该内体亚群形成和维持所需的参与者。