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P53 deficiency affects cholesterol esterification to exacerbate hepatocarcinogenesis
Hepatology ( IF 12.9 ) Pub Date : 2022-04-10 , DOI: 10.1002/hep.32518
Yahui Zhu 1, 2, 3 , Li Gu 1, 2 , Xi Lin 1, 2 , Xinyi Zhou 1, 2 , Bingjun Lu 1, 2 , Cheng Liu 1, 2 , Yajun Li 1, 2 , Edward V Prochownik 4 , Michael Karin 5 , Fubing Wang 6 , Youjun Li 1, 2
Affiliation  

Cholesterol ester (CE) biosynthesis and homeostasis play critical roles in many cancers, including HCC, but their exact mechanistic contributions to HCC disease development require further study.

中文翻译:


P53缺乏影响胆固醇酯化加剧肝癌发生



胆固醇酯 (CE) 生物合成和稳态在包括 HCC 在内的许多癌症中发挥着关键作用,但它们对 HCC 疾病发展的确切机制贡献需要进一步研究。
更新日期:2022-04-10
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