To achieve health equity, we advocate for the overrepresentation of particular racial and ethnic minority groups so that analyses of group-specific treatment effects can be optimally powered. A paradigm shift is needed across multiple stakeholders, as well as in the engagement of community programmes, the role of investigators from racial and ethnic minority backgrounds and clinical trial regulations.

中文翻译：

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代表是否足够，还是我们应该以公平包容为目标？

为了实现健康公平，我们提倡特定种族和少数族裔群体的代表性过高，以便对特定群体治疗效果的分析能够得到最佳支持。需要在多个利益相关者之间进行范式转变，以及在社区项目的参与、来自种族和少数族裔背景的调查人员的作用以及临床试验法规方面。