Proteins, the building blocks of life, often form large assemblies to perform their function but are traditionally studied separately in structural biology. In this issue of Structure, Skalidis et al. (2022) present a workflow to identify members of intact protein communities and solve their structures de novo to near-atomic resolution.

中文翻译：

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用于细胞提取物结构研究的人工智能辅助冷冻电镜管道

蛋白质是生命的组成部分，通常会形成大型组件来发挥其功能，但传统上在结构生物学中是单独研究的。在本期结构中，Skalidis 等人。（2022 年）提出了一种工作流程，用于识别完整蛋白质群落的成员并将其结构从头解析到近原子分辨率。