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Stem cell-derived β cells go in monkeys
Cell Stem Cell ( IF 19.8 ) Pub Date : 2022-04-07 , DOI: 10.1016/j.stem.2022.03.010
Anne Grapin-Botton 1 , Barbara Ludwig 2
Affiliation  

Du et al. transplanted β cells derived from pluripotent stem cells in diabetic monkeys for the first time, as an intermediate stage toward clinical translation. They observed benefits unfolding over months but also observed immune rejection of the grafts by 5–6 months.



中文翻译:

干细胞衍生的β细胞进入猴子体内

杜等人。首次将源自多能干细胞的β细胞移植到糖尿病猴体内,作为临床转化的中间阶段。他们观察到益处在数月内逐渐显现,但也观察到移植物的免疫排斥反应在 5-6 个月内出现。

更新日期:2022-04-07
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