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Quercetin Impedes Th17 Cell Differentiation to Mitigate Arthritis Involving PPARγ-Driven Transactivation of SOCS3 and Redistribution Corepressor SMRT from PPARγ to STAT3
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-04-05 , DOI: 10.1002/mnfr.202100826
Yan Yang 1, 2 , Gao-Na Shi 1 , Xin Wu 3 , Min Xu 2 , Cheng-Juan Chen 1 , Yu Zhou 1 , Ya-Zi Wei 1 , Lei Wu 1 , Fen-Fang Cui 2 , Lan Sun 1 , Tian-Tai Zhang 1
Affiliation  

Quercetin (QU) is one of the most abundant flavonoids in plants and has attracted the attention of researchers because of its remarkable antirheumatoid arthritis (RA) effects and extremely low adverse reactions. However, the underlying mechanism needs further study.

中文翻译:

槲皮素阻碍 Th17 细胞分化以减轻关节炎,包括 PPARγ 驱动的 SOCS3 反式激活和从 PPARγ 到 STAT3 的再分配辅阻遏物 SMRT

槲皮素(QU)是植物中含量最丰富的黄酮类化合物之一,因其显着的抗风湿性关节炎(RA)作用和极低的不良反应而引起了研究人员的关注。然而,潜在的机制需要进一步研究。
更新日期:2022-04-05
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