Trans‑10‑Hydroxy‑2-Decenoic Acid Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice via Regulating the Inflammasome-Mediated Pyroptotic Pathway and Enhancing Colonic Barrier Function,Molecular Nutrition & Food Research

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Trans‑10‑Hydroxy‑2-Decenoic Acid Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice via Regulating the Inflammasome-Mediated Pyroptotic Pathway and Enhancing Colonic Barrier Function
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-04-04 , DOI: 10.1002/mnfr.202100821
Shanshan Huang _{1,

2} , Ranran Tao _{1,

2} , Jiefei Zhou _{1,

2} , Linxi Qian _{1,

2} , Jiang Wu ₃

Affiliation

The objective of this study is to explore the effects of 10-hydroxy-2-decenoic acid (10-HDA), the major fatty acid in royal jelly, on dextran sodium sulfate (DSS)-induced mice ulcerative colitis (UC) and its potential mechanism of action.

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