The burgeoning field of intratumoural microbiome research has been driven by advances in next-generation sequencing technologies, with compelling evidence on the role of the microbiota in cancer initiation, progression and patient response to treatment. Here, we discuss new concepts of the tumour-associated microbiota and what is needed to advance the translational impact of these findings in gastrointestinal cancers.

中文翻译：

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肿瘤相关微生物组


新一代测序技术的进步推动了肿瘤内微生物组研究的蓬勃发展，有令人信服的证据表明微生物组在癌症发生、进展和患者对治疗的反应中的作用。在这里，我们讨论肿瘤相关微生物群的新概念，以及如何推动这些发现对胃肠道癌症的转化影响。