Over the past decade, iterative improvements to models predicting breast cancer risk have primarily come from new information about genetic risk factors and improvements to mammogram-based risk scores. Epigenetic risk factors offer some potential to further improve risk stratification. However, the recently developed DNA methylation score (the WID-BC index) is not yet convincing for predicting breast cancer risk.

中文翻译：

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利用表观遗传风险因素改善乳腺癌风险预测

在过去十年中，预测乳腺癌风险的模型的迭代改进主要来自有关遗传风险因素的新信息和基于乳房 X 光检查的风险评分的改进。表观遗传风险因素为进一步改善风险分层提供了一些潜力。然而，最近开发的 DNA 甲基化评分（WID-BC 指数）对于预测乳腺癌风险尚不能令人信服。