Asymmetric catalysis has continued to enable the preparation of optically active natural products over the past decade. This minireview summarizes progress in the catalytic enantioselective total synthesis of complex monoterpenoid indole alkaloids covering the reports from 2019 to June 2021. In particular, generation of the key chiral stereogenic centers with metal catalysts and organocatalysts has been highlighted, showcasing the power of asymmetric catalysis protocols in accessing complex molecular architectures.

中文翻译：

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不对称催化合成单萜吲哚生物碱的最新进展

在过去的十年中，不对称催化继续使光学活性天然产物的制备成为可能。本综述总结了 2019 年至 2021 年 6 月报道的复杂单萜吲哚生物碱的催化对映选择性全合成进展。特别强调了用金属催化剂和有机催化剂生成关键手性立体中心，展示了不对称催化协议的力量访问复杂的分子结构。