Utilization of Nanoparticles, Nanodevices, and Nanotechnology in the Treatment Course of Cutaneous Melanoma,Advanced Therapeutics

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Utilization of Nanoparticles, Nanodevices, and Nanotechnology in the Treatment Course of Cutaneous Melanoma
Advanced Therapeutics ( IF 3.7 ) Pub Date : 2022-03-23 , DOI: 10.1002/adtp.202100208
Thomas Hartmann ₁ , Rebecca Perron ₁ , Mehdi Razavi _{1,

2,

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Affiliation

Melanoma is a highly lethal form of skin cancer caused by rapid proliferation of melanocytes, pigment-producing cells of the skin. Despite continued advancements, current diagnostic and treatment techniques have been inadequate in decreasing the global health burden of this disease. Therefore, increased research has gone into solving these hindrances to treatment, with nanomedicine offering many promising solutions. In this review, different subtypes of nanomedicine will be discussed along with their clinical utility in relation to melanoma. First, risk factors, pathogenesis, and current therapeutic techniques relating to melanoma will be summarized and discussed. Then, the main types of nanomedicine and their use in treating melanoma will be discussed including nanoparticles, nanodevices, and nanotechnological tools in drug delivery and diagnosis.

中文翻译：

纳米粒子、纳米器件和纳米技术在皮肤黑色素瘤治疗过程中的应用

黑色素瘤是一种高度致命的皮肤癌，由黑色素细胞（皮肤的色素生成细胞）快速增殖引起。尽管不断取得进步，但目前的诊断和治疗技术不足以减轻这种疾病的全球健康负担。因此，越来越多的研究致力于解决这些治疗障碍，纳米医学提供了许多有希望的解决方案。在这篇综述中，将讨论不同亚型的纳米药物及其在黑色素瘤方面的临床应用。首先，将总结和讨论与黑色素瘤相关的危险因素、发病机制和当前的治疗技术。然后，将讨论纳米药物的主要类型及其在治疗黑色素瘤中的用途，包括纳米粒子、纳米器件和纳米技术工具在药物输送和诊断中的应用。

更新日期：2022-03-23

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