The study of human reactive astrocytes has been limited by resource availability. In this issue, Cvetkovic et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202107135) develop multicellular organoid systems containing mature astrocytes to study the dynamics of human astrocytes reactivity and its downstream effects on neuronal activity.

中文翻译：

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调整神经类器官来模拟人类反应性星形胶质细胞

人类反应性星形胶质细胞的研究受到资源可用性的限制。在本期中，Cvetkovic 等人。(2022. J. Cell Biol.https://doi.org/10.1083/jcb.202107135) 开发含有成熟星形胶质细胞的多细胞类器官系统，以研究人类星形胶质细胞反应性的动态及其对神经元活动的下游影响。