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Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room
Food and Environmental Virology ( IF 3.4 ) Pub Date : 2022-03-20 , DOI: 10.1007/s12560-022-09519-y
Marie Estienney 1, 2 , Philippe Daval-Frerot 1 , Ludwig-Serge Aho-Glélé 3 , Lionel Piroth 4 , Pascal Stabile 5 , Jean-Yves Gerbet 5 , Romain Rouleau 6 , Alexis de Rougemont 1, 2 , Gaël Belliot 1, 2
Affiliation  

Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided promising results in laboratory assays. Here, we evaluate the efficacy of a hydrogen peroxide nebulizer for the inactivation of surrogate MS2 bacteriophage and murine norovirus (MNV) in a patient waiting room and the fully equipped cabin of a medical ambulance. We observed an average 3 log10 titer reduction in both settings, which represents the destruction of over 106 and 109 infectious particles of MNV and MS2 per cm2, respectively. The potential for viral exposure is high for health workers when disinfecting confined and cluttered spaces, so the use of a hydrogen peroxide mist might offer an affordable and efficient solution to minimize the risk of viral contaminations.



中文翻译:

使用过氧化氢雾化器对紧急救护车和医院候诊室进行病毒消毒

医院设施和救护车的消毒是打破病毒病原体传播链的重要问题。过氧化氢在实验室测定中提供了有希望的结果。在这里,我们评估了过氧化氢雾化器在患者候诊室和设备齐全的医疗救护车舱内灭活替代 MS2 噬菌体和鼠诺如病毒 (MNV) 的功效。我们观察到两种设置中的平均 3 log 10滴度降低,这表示每 cm 2破坏超过 10 6和 10 9的 MNV 和 MS2 传染性颗粒, 分别。在对狭窄和杂乱的空间进行消毒时,卫生工作者接触病毒的可能性很高,因此使用过氧化氢雾剂可能会提供一种经济实惠且有效的解决方案,以最大限度地降低病毒污染的风险。

更新日期:2022-03-20
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