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Medical error in treatment of Amanita phalloides poisoning in pre-hospital care
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine ( IF 3.0 ) Pub Date : 2022-03-19 , DOI: 10.1186/s13049-022-01008-2
Anna Smędra 1 , Katarzyna Wochna 1 , Dariusz Zawadzki 2 , Jarosław Berent 1
Affiliation  

Geopolitical and climate changes form the background of the current migration crisis. It has many faces. One of them are the tragic cases of poisoning of refugees due to eating wild forest mushrooms for socioeconomic reasons in the Western and Northern European countries. The most serious food poisonings in Europe, but not only, are caused by lamellar mushrooms, the most dangerous being Amanita phalloides. Its poisonous properties can be attributed to α-amanitin, an RNA polymerase II inhibitor. Unfortunately, as it is characterized by a delayed onset of symptoms, A. phalloides poisoning has a high risk of complications. Our article presents a case of A. phalloides poisoning in a 28-year-old man, in which the responding medical emergency unit made errors in diagnosis and treatment. Since the correct diagnosis was made too late, the typical treatment of A. phalloides poisoning was ineffective. The patient suffered a life-threatening liver failure and needed liver transplant from a deceased donor. Mushroom poisoning is a particularly important problem not only in countries with a mushroom picking tradition, but also—due to the inflow of refugees—in countries where mushroom poisoning was very rare until recently. In such cases it is crucial to quickly implement the correct procedure, as this can prevent the need for liver transplant or even death. This is a particularly important consideration for the first medical professionals to contact the patient, especially in cases where the patient reports mushrooms consumption and presents alarming symptoms of the gastrointestinal tract. Such situations cannot be underestimated and ignored.

中文翻译:


鬼笔伞菌中毒院前急救中的医疗失误



地缘政治和气候变化构成了当前移民危机的背景。它有很多面孔。其中之一是西欧和北欧国家因社会经济原因而导致难民因食用野生森林蘑菇而中毒的悲惨案例。欧洲最严重的食物中毒,但不仅仅是由层状蘑菇引起的,其中最危险的是鬼笔伞菌。其有毒特性可归因于 α-鹅膏蕈碱,一种 RNA 聚合酶 II 抑制剂。不幸的是,由于其症状出现较晚,因此鬼笔环线虫中毒出现并发症的风险很高。我们的文章介绍了一名 28 岁男性的鬼笔环线虫中毒案例,该案例中医疗急救部门在诊断和治疗上出现了错误。由于正确诊断为时已晚,鬼笔环线虫中毒的典型治疗无效。该患者患有危及生命的肝功能衰竭,需要从已故捐赠者那里进行肝脏移植。蘑菇中毒不仅在具有蘑菇采摘传统的国家是一个特别重要的问题,而且由于难民的涌入,在直到最近蘑菇中毒事件还非常罕见的国家也是如此。在这种情况下,快速实施正确的手术至关重要,因为这可以防止肝移植甚至死亡。对于第一个接触患者的医疗专业人员来说,这是一个特别重要的考虑因素,特别是在患者报告食用蘑菇并出现令人震惊的胃肠道症状的情况下。这种情况不容低估和忽视。
更新日期:2022-03-19
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