The aim of the study was to conduct a literature review on growth hormone therapy in short-stature patients with kyphoscoliosis. The search strategy was performed in which all the relevant papers published in 20 years were included on Pub Med, Central, and Google scholar by using keywords short stature, growth hormones, adverse events of growth hormones in kyphoscoliosis, safety. The study investigation supports the idea that giving human growth hormone (HGH) to a diverse population of short-statured children does not enhance the occurrence of scoliosis. Patients on HGH therapy for progressing scoliosis had syndromes in which scoliosis was more prevalent in an age-matched group. Short stature attributed to progressive growth failure is prevalent in all mucopolysaccharidosis (MPS) disorders, as per the existing research on growth and growth hormone in MPS. MPS should be explored in children who are being tested for short stature since growth failure might be the presenting symptom.

中文翻译：

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矮小脊柱侧凸患者的生长激素治疗：文献综述。

本研究的目的是对矮小脊柱侧凸患者的生长激素治疗进行文献回顾。采用关键词身材矮小、生长激素、生长激素对脊柱后凸畸形的不良事件、安全性等关键词进行检索，将20年来发表的所有相关论文收录在Pub Med、Central和Google学术上。该研究调查支持这样一种观点，即向不同的矮身高儿童群体提供人类生长激素 (HGH) 并不会增加脊柱侧弯的发生率。因脊柱侧弯进展而接受 HGH 治疗的患者出现了脊柱侧弯在年龄匹配组中更为普遍的综合征。由进行性生长障碍引起的身材矮小在所有粘多糖贮积症 (MPS) 疾病中普遍存在，根据现有的关于 MPS 中生长和生长激素的研究。应该在正在接受身材矮小测试的儿童中探索 MPS，因为生长障碍可能是表现症状。