Introduction Prenatal ultrasound-guided laser coagulation (USLC) for complicated bronchopulmonary sequestrations has been described but a consensus on the procedure and on the following management is still lacking. We present our experience and provide a literature review. Methods Retrospective review of patients treated in our center. Literature review and combined analysis of perinatal data were performed. Results Five cases were treated at our center, all presenting with severe hydrothorax. Four met the criteria for fetal hydrops. Four cases underwent postnatal computed tomography (CT) scan: in one case, there was no evidence of persistent bronchopulmonary sequestration. The other three underwent thoracoscopic resection, in two, a viable sequestration was found. Including our series, 57 cases have been reported, with no mortality and a success rate of 94.7%. Mean gestational age (GA) at the procedure was 28 ± 3.4 weeks and mean GA at birth and birth weight (BW) were 38.6 ± 2.3 weeks and 3,276 ± 519.8 g, respectively. In 80.6% of the cases investigated postnatally, a residual mass was found, 50% of cases who showed prenatal arterial flow cessation had a persistent sequestration postnatally, and 26.3% of cases underwent postnatal sequestrectomy. Both patients in our series had pathology examination confirming a viable bronchopulmonary sequestration. Conclusion Prenatal USLC seems to be a valid option for bronchopulmonary sequestration complicated by severe hydrothorax and/or fetal hydrops. Authors believe that this procedure should aim to reverse fetal distress and allow pregnancy continuation, and it should not be considered a definitive treatment. The currently available data do not support changes of the common postnatal management.

中文翻译：

---

宫内超声引导下激光凝固术作为治疗产前复杂性支气管肺隔离症的第一步：我们的经验和文献回顾

简介 产前超声引导激光凝固术 (USLC) 用于复杂的支气管肺隔离症已有描述，但仍缺乏对该程序和后续管理的共识。我们介绍我们的经验并提供文献综述。方法对在我中心收治的患者进行回顾性分析。对围产期数据进行了文献回顾和综合分析。结果我中心收治5例，均表现为重度胸水。四个符合胎儿水肿的标准。4 例患者接受了产后计算机断层扫描 (CT) 扫描：其中 1 例没有持续性支气管肺隔离症的证据。其他三人接受了胸腔镜切除术，其中两人发现了可行的隔离。包括我们的系列在内，已经报告了 57 个案例，无死亡率，成功率为 94.7%。手术时的平均胎龄 (GA) 为 28 ± 3.4 周，出生时的平均胎龄和出生体重 (BW) 分别为 38.6 ± 2.3 周和 3,276 ± 519.8 g。在产后调查的病例中，80.6% 发现残留肿块，50% 显示产前动脉血流停止的病例在出生后有持续性隔离，26.3% 的病例接受了出生后死骨切除术。我们系列中的两名患者均进行了病理检查，证实存在可行的支气管肺隔离症。结论 产前 USLC 似乎是并发严重胸水和/或胎儿水肿的支气管肺隔离症的有效选择。作者认为，该手术的目的应该是逆转胎儿窘迫并允许继续妊娠，不应将其视为最终治疗方法。