Background: Cystic fibrosis (CF) is a genetic disorder, in which defective clearance of airway secretions leads to progressive lung function loss. Inhaled mannitol is used to increase sputum and mucociliary clearance. There are little data from real-world studies on the effectiveness of mannitol in children. Our objective was to evaluate the spirometry and clinical results of mannitol in pediatric patients.

中文翻译：

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吸入干粉甘露醇治疗小儿囊性纤维化患者：真实环境中临床数据的评估

背景：囊性纤维化（CF）是一种遗传性疾病，其中气道分泌物清除缺陷导致进行性肺功能丧失。吸入甘露醇用于增加痰液和粘液纤毛的清除。关于甘露醇对儿童的有效性的真实研究数据很少。我们的目的是评估甘露醇在儿科患者中的肺活量测定和临床结果。