Heterogeneous Microfluidic Reactors: A Review and an Insight of Enzymatic Reactions,ChemBioEng Reviews

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Heterogeneous Microfluidic Reactors: A Review and an Insight of Enzymatic Reactions
ChemBioEng Reviews ( IF 6.2 ) Pub Date : 2022-03-09 , DOI: 10.1002/cben.202100058
Fiona W. M. Ling _{1,

2} , Hayder A. Abdulbari _{1,

2} , Sim Yee Chin ₂

Affiliation

Heterogeneous reactions are considered the heart of chemical synthesis with numerous industrial applications due to their high conversion rates and low reaction time. On the other hand, the performance of heterogeneous reactions suffers from several drawbacks such as lower product selectivity and high mass transfer resistance that, in many cases, reduce the reaction rate. The efficiency of various conventional mixing techniques in heterogeneous reactors is believed to play a critical role in controlling the product quality and mass transfer rates besides other essential factors. Microfluidics technology provides a unique opportunity to revisit many established heterogeneous reaction processes to optimize and understand the reaction mechanisms. The unique flow conditions in microflow systems provide an excellent platform for exploring the effect of high-precision micromixing techniques on reaction rates and productivities. Recent advances in microreactor technology in general and specifically heterogeneous reactions in microflow systems with an insight on the enzymatic reactions in microreactors are reviewed.

中文翻译：

多相微流控反应器：酶反应的回顾和洞察

多相反应因其高转化率和低反应时间而被认为是化学合成的核心，具有许多工业应用。另一方面，多相反应的性能存在一些缺点，例如较低的产物选择性和较高的传质阻力，在许多情况下会降低反应速率。除了其他重要因素外，人们认为非均相反应器中各种常规混合技术的效率在控制产品质量和传质速率方面起着关键作用。微流体技术提供了一个独特的机会来重新审视许多已建立的非均相反应过程，以优化和了解反应机制。微流系统中独特的流动条件为探索高精度微混合技术对反应速率和生产率的影响提供了一个极好的平台。回顾了微反应器技术的最新进展，特别是微流系统中的非均相反应，并对微反应器中的酶促反应进行了深入了解。

更新日期：2022-03-09

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