Abstract

Quercetin is a plant-derived polyphenol flavonoid that has been proven to be effective for many diseases. However, the mechanism and in vivo metabolism of quercetin remains to be clarified. It achieves a wide range of biological effects through various metabolites, gut microbiota and its metabolites, systemic mediators produced by inflammation and oxidation, as well as by multiple mechanisms. The all-round disease treatment of quercetin is achieved through the organic combination of multiple channels. Therefore, this article clarifies the metabolic process of quercetin in the body, and explores the new pattern of action of quercetin in the treatment of diseases.

中文翻译：

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基于体内药代动力学和多靶点机制的槲皮素潜在生物学效应

摘要

槲皮素是一种植物来源的多酚类黄酮，已被证明对许多疾病有效。然而，槲皮素的作用机制和体内代谢仍有待阐明。它通过各种代谢物、肠道菌群及其代谢物、炎症和氧化产生的系统性介质以及多种机制实现广泛的生物学效应。槲皮素的全方位疾病治疗是通过多渠道的有机结合来实现的。因此，本文阐明了槲皮素在体内的代谢过程，探索槲皮素治疗疾病的新作用模式。