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TNF inhibition enhances depletion of synovial fibroblasts by ferroptosis
Nature Reviews Rheumatology ( IF 29.4 ) Pub Date : 2022-03-10 , DOI: 10.1038/s41584-022-00769-5 Robert Phillips 1
Nature Reviews Rheumatology ( IF 29.4 ) Pub Date : 2022-03-10 , DOI: 10.1038/s41584-022-00769-5 Robert Phillips 1
Affiliation
New research shows that induction of ferroptosis can deplete synovial fibroblasts that are activated in rheumatoid arthritis, and that co-treatment with a TNF inhibitor enhances this depletion.
中文翻译:
TNF抑制通过铁死亡增强滑膜成纤维细胞的消耗
新的研究表明,铁死亡的诱导可以消耗在类风湿性关节炎中被激活的滑膜成纤维细胞,并且与 TNF 抑制剂的共同治疗会增强这种消耗。
更新日期:2022-03-10
中文翻译:
TNF抑制通过铁死亡增强滑膜成纤维细胞的消耗
新的研究表明,铁死亡的诱导可以消耗在类风湿性关节炎中被激活的滑膜成纤维细胞,并且与 TNF 抑制剂的共同治疗会增强这种消耗。