Many aspects of cell signaling are controlled by lipids. Several signaling lipids have been functionalized with an azobenzene photoswitch to control underlying signaling dynamics with light. Herein, we provide an overview of signaling photolipids developed to date focusing on their biological applications. These include immunomodulation, kinase translocation, apoptosis, ion channel activation, G-protein coupled receptor activation, and neurogenesis.

中文翻译：

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光控脂质对细胞信号传导的光药理学控制

细胞信号传导的许多方面都受脂质控制。几种信号脂质已经用偶氮苯光开关功能化，以控制光的潜在信号动力学。在此，我们概述了迄今为止开发的信号光脂，重点是它们的生物学应用。这些包括免疫调节、激酶易位、细胞凋亡、离子通道激活、G 蛋白偶联受体激活和神经发生。