Objectives: Intimate partner violence (IPV) against pregnant or human immunodeficiency virus (HIV)-positive women have been previously studied. However, data on the impact of IPV on HIV-positive pregnant women have not been systematically synthesized. We performed a meta-analysis to explore this issue and provide evidence regarding IPV prevention and HIV infection control. Method: The PubMed, Web of Science, Cochrane Library, and Embase databases were systematically searched. Studies that quantitatively assessed the association between IPV and its adverse impact on HIV-positive women during pregnancy and post-partum were eligible for inclusion. Pooled odds ratios (ORs) were calculated. Findings: Eight studies were identified to meet our eligibility criteria. The adverse impacts of IPV against HIV-positive pregnant women mainly included nonadherence to maternal antiretroviral treatment during pregnancy, nondisclosure of HIV-positive status to male partners, nonadherence to infant antiretroviral prophylaxis, and antenatal depression. IPV caused a 180% and 145% increase in the odds of antenatal depression and nonadherence to infant antiretroviral prophylaxis, respectively, among HIV-positive women, compared to the odds of their IPV-free counterparts [OR = 2.80, 95% confidence interval (CI): 1.66–4.74; OR = 2.45, 95% CI: 1.40–4.27]. Conclusion: Limited evidence has suggested that IPV against HIV-positive pregnant women caused maternal depression during pregnancy and led to the possible failure of HIV prophylaxis adherence in infants. Interventions to address IPV may ultimately reduce the risk of depression-related adverse birth outcomes and vertical transmission in infants exposed to maternal HIV. Prevention and control against IPV should be developed for HIV-positive pregnant women.

目的：之前已经研究过针对怀孕或人类免疫缺陷病毒 (HIV) 阳性妇女的亲密伴侣暴力 (IPV)。然而，关于 IPV 对 HIV 阳性孕妇影响的数据尚未得到系统综合。我们进行了一项荟萃分析来探讨这个问题，并提供有关 IPV 预防和 HIV 感染控制的证据。方法：系统检索了 PubMed、Web of Science、Cochrane 图书馆和 Embase 数据库。定量评估 IPV 与其对怀孕和产后 HIV 阳性妇女的不利影响之间的关联的研究符合纳入标准。计算汇总优势比 (OR)。发现：确定了八项研究符合我们的资格标准。IPV 对 HIV 阳性孕妇的不良影响主要包括孕期不依从母体抗逆转录病毒治疗、未向男性伴侣披露 HIV 阳性状况、不依从婴儿抗逆转录病毒预防和产前抑郁。与未接受 IPV 的女性相比，IPV 导致 HIV 阳性女性产前抑郁症和不依从婴儿抗逆转录病毒预防的几率分别增加了 180% 和 145% [OR = 2.80, 95% 置信区间（ CI): 1.66–4.74; OR = 2.45, 95% CI: 1.40–4.27]。结论：有限的证据表明，针对 HIV 阳性孕妇的 IPV 会导致孕期母体抑郁，并导致婴儿可能无法坚持 HIV 预防。解决 IPV 的干预措施可能最终降低暴露于母体 HIV 的婴儿中与抑郁症相关的不良出生结局和垂直传播的风险。应针对 HIV 阳性孕妇开展 IPV 的预防和控制。