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Human 8-cell-like cells discovered
Cell Stem Cell ( IF 19.8 ) Pub Date : 2022-03-03 , DOI: 10.1016/j.stem.2022.01.015
Bradley P Balaton 1 , Vincent Pasque 1
Affiliation  

Human naive pluripotent stem cells have the remarkable ability to generate blastoids comprising trophectoderm, epiblast, and hypoblast-like cells. In this issue, Taubenschmid-Stowers et al. (2022) show that human naive pluripotent stem cell cultures contain cells that resemble the 8-cell human embryo, providing a model to study zygotic genome activation.



中文翻译:

发现人类 8 细胞样细胞

人类幼稚多能干细胞具有产生包括滋养外胚层、外胚层和下胚层样细胞的类胚层的显着能力。在这个问题上,Taubenschmid-Stowers 等人。(2022) 表明人类幼稚多能干细胞培养物含有类似于 8 细胞人类胚胎的细胞,为研究合子基因组激活提供了模型。

更新日期:2022-03-03
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