Periodontitis and chronic kidney disease are chronic conditions with high community prevalence across the world. Patients with chronic kidney disease have been noted to have a high burden of periodontitis, and several shared risk factors have been associated with the prevalence and severity of both conditions. However, the precise relationship between the two conditions, and the extent to which each may contribute to the development of the other, remains a matter of debate. The goals of the present work were to: (a) provide the most current and relevant literature overview of the association between periodontitis and chronic kidney disease; (b) explore mechanisms underlying this association; and (c) determine if evidence exists for an independent association between these conditions. We also assessed whether improved oral hygiene and periodontal treatment could reduce the risk of developing chronic kidney disease and, if so, what protocols these strategies involve. Finally, we aimed to reveal gaps in our current knowledge to delineate the directions of future research. Although the exact relationship between these two conditions has not yet been defined, we highlight the importance of the interprofessional interaction between dental practitioners and the nephrology team and the importance of oral health assessment in the management of chronic kidney disease.

中文翻译：

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牙周炎与慢性肾脏病的关系

牙周炎和慢性肾脏病是全球社区患病率高的慢性疾病。已经注意到患有慢性肾病的患者牙周炎的负担很高，并且一些共同的风险因素与这两种疾病的流行和严重程度有关。然而，这两种情况之间的确切关系，以及每种情况对另一种情况的影响程度，仍然是一个有争议的问题。本工作的目标是： (a) 提供关于牙周炎与慢性肾病之间关系的最新和相关文献综述；(b) 探索这种关联的基础机制；(c) 确定这些条件之间是否存在独立关联的证据。我们还评估了改善口腔卫生和牙周治疗是否可以降低患慢性肾病的风险，如果可以，这些策略涉及哪些方案。最后，我们旨在揭示我们当前知识的差距，以描绘未来研究的方向。虽然这两种情况之间的确切关系尚未确定，但我们强调了牙科医生和肾脏病学团队之间跨专业互动的重要性，以及口腔健康评估在慢性肾病管理中的重要性。