Transitioning to college during the novel coronavirus disease 2019 (COVID-19) pandemic may increase risk for alcohol use and mental health problems. We examined how COVID-19 related stressors and parent–child relationships are independently and interactively associated with alcohol use and mental health profiles in a sample of first-year college students (N = 425, 34.8% Hispanic/Latinx; 74.9% female) who completed an online survey in October 2020. Latent profile analysis identified four profiles: well-adjusted (53.2%), mental health problems only (21.6%), alcohol use only (17.4%), and comorbid (7.8%). COVID-19 related stressful events increased risk of being in the alcohol use only and comorbid profiles, whereas COVID-19 related worries increased risk of being in the mental health problems only profile. Parent–child relationship quality lowered risk of being in the mental health problems only and the comorbid profiles. In addition, parent–child relationship quality moderated the role of COVID-19 related worries such that COVID-19 related worries were associated with lower odds of being in the comorbid profile when parent–child relationship quality was high but not when parent–child relationship quality was low. Strengthening parent–child relationship quality appears important for promoting college students’ well-being.

在 2019 年新型冠状病毒病 (COVID-19) 大流行期间过渡到大学可能会增加饮酒和心理健康问题的风险。我们研究了与 COVID-19 相关的压力源和亲子关系如何与酒精使用和心理健康状况独立和交互相关，在一年级大学生样本中（N = 425，34.8% 西班牙裔/拉丁裔；74.9% 女性）谁2020 年 10 月完成了一项在线调查。潜在概况分析确定了四个概况：调整良好 (53.2%)、仅存在心理健康问题 (21.6%)、仅饮酒 (17.4%) 和合并症 (7.8%)。COVID-19 相关的压力事件增加了仅使用酒精和合并症的风险，而与 COVID-19 相关的担忧增加了仅存在心理健康问题的风险。亲子关系质量降低了仅存在心理健康问题和合并症的风险。此外，亲子关系质量缓和了与 COVID-19 相关的担忧的作用，因此当亲子关系质量较高时，与 COVID-19 相关的担忧与较低的合并症几率相关，而在亲子关系时则不然质量低。加强亲子关系质量对于促进大学生幸福感似乎很重要。亲子关系质量缓和了与 COVID-19 相关的担忧的作用，因此当亲子关系质量较高时，与 COVID-19 相关的担忧与较低的合并症几率相关，而当亲子关系质量较低时则不然. 加强亲子关系质量对于促进大学生幸福感似乎很重要。亲子关系质量缓和了与 COVID-19 相关的担忧的作用，因此当亲子关系质量较高时，与 COVID-19 相关的担忧与较低的合并症几率相关，而当亲子关系质量较低时则不然. 加强亲子关系质量对于促进大学生幸福感似乎很重要。