Abstract

BACKGROUND:

Patients with temporomandibular disorders (TMD) mostly suffer from muscle-related pain. Several conservative interventions have been suggested as treatments for TMD in the last years.

OBJECTIVE:

The aim of this systematic review with meta-analysis was to assess the efficacy of rehabilitative approaches in reducing pain in patients with muscle-related TMD.

METHODS:

PubMed, Scopus, and Web of Science were systematically searched from inception until April 28th, 2021 to identify randomized controlled trials (RCTs) presenting: patients with painful muscle-related TMD; rehabilitative approaches as interventions; placebo or sham treatment as comparisons; pain intensity, using visual analogue scale as outcome. A meta-analysis was performed to evaluate the overall effect on painful muscle-related TMD patients. PROSPERO registration number of this systematic review is CRD42021251904.

RESULTS:

Out of 1997 papers suitable for title/abstract screening, 189 articles were assessed for eligibility. Sixteen RCTs were included and most of them (n= 6, 37.5%) investigated the effects of the laser therapy. The meta-analysis revealed that rehabilitative interventions had a significant overall effect size (ES) of 1.44 (p< 0.0001) in decreasing pain in patients with muscle-related disorders.

CONCLUSION:

Findings of this systematic review with meta-analysis suggested that rehabilitative approaches might be effective in reducing pain in muscle-related TMD patients. However, the low number of RCTs evaluating conservative approaches might impair the synthesis of evidence regarding the different techniques, calling for caution in the interpretation of these results.

中文翻译：

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康复治疗对减轻肌肉相关颞下颌关节疾病疼痛的疗效：随机对照试验的系统评价和荟萃分析

摘要

背景：

颞下颌关节紊乱病 (TMD) 患者大多患有与肌肉相关的疼痛。在过去的几年中，一些保守的干预措施被建议作为 TMD 的治疗方法。

客观的：

此项荟萃分析系统评价的目的是评估康复方法在减轻肌肉相关 TMD 患者疼痛方面的功效。

方法：

从开始到 4 月 28 日，系统地搜索了 PubMed、Scopus 和 Web of Scienceth, 2021 年确定随机对照试验 (RCT) 呈现：肌肉相关 TMD 疼痛患者；康复方法作为干预措施；安慰剂或假治疗作为比较；疼痛强度，使用视觉模拟量表作为结果。进行了一项荟萃分析，以评估对疼痛性肌肉相关 TMD 患者的总体影响。本系统评价的PROSPERO注册号为CRD42021251904。

结果：

在 1997 篇适合标题/摘要筛选的论文中，有 189 篇被评估为合格。纳入了 16 项 RCT，其中大部分（n=6, 37.5%) 研究了激光治疗的效果。荟萃分析显示，康复干预的总体效应量（ES）显着为 1.44（p<0.0001) 减轻肌肉相关疾病患者的疼痛。

结论：

这项系统评价和荟萃分析的结果表明，康复方法可能有效减轻肌肉相关 TMD 患者的疼痛。然而，评估保守方法的随机对照试验数量较少可能会损害有关不同技术的证据的综合，因此在解释这些结果时需要谨慎。