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Platelet phagocytosis by leukocytes in a patient with cerebral hemorrhage and thrombocytopenia caused by gram-negative bacterial infection
Journal of International Medical Research ( IF 1.4 ) Pub Date : 2022-02-25 , DOI: 10.1177/03000605221079102
Xiuji Wu 1 , Youjun Li 2 , Xiaoyang Yang 3
Affiliation  

Bacteria-induced thrombocytopenia is a common clinical disease that is often ignored by clinical and scientific research. Thus, exploring the mechanism and principle of bacteria-induced thrombocytopenia could facilitate the development of new diagnostic, preventative, and treatment modalities for thrombocytopenia. This case report describes a case of platelet phagocytosis by neutrophils and monocytes in a patient with cerebral hemorrhage and thrombocytopenia caused by gram-negative bacterial infection. After the infection was eradicated, platelet phagocytosis was alleviated, and his platelet count normalized. Cellular immunity may be an important cause of bacteria-induced thrombocytopenia in patients with cerebral hemorrhage.



中文翻译:

革兰氏阴性菌感染所致脑出血合并血小板减少症患者白细胞吞噬血小板作用

细菌性血小板减少症是临床和科学研究常被忽视的常见临床疾病。因此,探索细菌性血小板减少症的机制和原理有助于开发新的血小板减少症诊断、预防和治疗方式。本病例报道一例革兰氏阴性菌感染所致脑出血和血小板减少症患者的中性粒细胞和单核细胞吞噬血小板的病例。感染根除后,血小板吞噬功能减轻,血小板计数恢复正常。细胞免疫可能是脑出血患者细菌性血小板减少症的重要原因。

更新日期:2022-02-25
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