The decrease in the number of satellite cells (SCs), contributing to myofibre formation and reconstitution, and their proliferative capacity, leads to muscle loss, a condition known as sarcopenia. Resistance training can prevent muscle loss; however, the underlying mechanisms of resistance training effects on SCs are not well understood. We therefore conducted a comprehensive transcriptome analysis of SCs in a mouse model.

中文翻译：

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阻力训练对老年小鼠卫星细胞的影响——转录组研究：对肌肉减少症的影响。

卫星细胞 (SC) 数量的减少，有助于肌纤维的形成和重建，以及它们的增殖能力，导致肌肉损失，这种情况称为少肌症。抗阻训练可以防止肌肉流失；然而，阻力训练对 SCs 影响的潜在机制尚不清楚。因此，我们在小鼠模型中对 SCs 进行了全面的转录组分析。