Background/aims This study investigated the risk factors for epiretinal membrane (ERM) in eyes with primary rhegmatogenous retinal detachment (RRD) that received silicone oil (SO) tamponade. Methods This retrospective analysis included 1140 patients (1140 eyes) with RRD who underwent primary vitrectomy and SO tamponade. The prevalence of ERM was estimated and possible risk factors (eg, type 2 diabetes, proliferative vitreoretinopathy (PVR), SO tamponade time (SOTT), photocoagulation, vitreous haemorrhage, choroidal detachment, cryotherapy and retinal tear size) were analysed via multiple logistic regression. Results The prevalence of ERM was 12.3% (140/1140), and the accuracy of preoperative ERM diagnosis was 40.5%. Multivariate logistic regression analysis showed that risk factors for ERM in eyes with SO tamponade included preoperative PVR (OR=4.336, 95% CI 2.533 to 7.424, p<0.001), type 2 diabetes (OR=3.996, 95% CI 2.013 to 7.932, p<0.001), photocoagulation energy (OR=1.785, 95% CI 1.306 to 2.439, p<0.001) and SOTT (OR=1.523, 95% CI 1.261 to 1.840, p<0.001). No statistically significant associations were observed between the incidence of ERM and other risk factors. Preoperative PVR showed the strongest association with risk of ERM. The risk of ERM was positively associated with SOTT, photocoagulation energy and preoperative PVR grade. Conclusion In eyes with RRD that received SO tamponade, the prevalence of ERM was 12.3%, while the accuracy of preoperative ERM diagnosis was low. Preoperative PVR, type 2 diabetes, photocoagulation energy and SOTT were the main risk factors for ERM. Data are available upon reasonable request. Data may be obtained from a third party and are not publicly available. All data relevant to the study are included in the article or uploaded as supplementary information. Not applicable.

中文翻译：

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原发性孔源性视网膜脱离硅油填充眼视网膜前膜的危险因素

背景/目的本研究调查了接受硅油（SO）填充的原发性孔源性视网膜脱离（RRD）眼的视网膜前膜（ERM）危险因素。方法 这项回顾性分析纳入了 1140 名 RRD 患者（1140 只眼睛），他们接受了初次玻璃体切除术和 SO 填塞。通过多元逻辑回归估计了 ERM 的患病率，并分析了可能的危险因素（例如 2 型糖尿病、增殖性玻璃体视网膜病变 (PVR)、SO 填塞时间 (SOTT)、光凝、玻璃体出血、脉络膜脱离、冷冻治疗和视网膜裂孔大小） 。结果ERM患病率为12.3%（140/1140），术前ERM诊断准确率为40.5%。多变量逻辑回归分析显示，SO 填塞眼发生 ERM 的危险因素包括术前 PVR（OR=4. 336，95% CI 2.533 至 7.424，p<0.001），2 型糖尿病（OR=3.996，95% CI 2.013 至 7.932，p<0.001），光凝能量（OR=1.785，95% CI 1.306 至 2.439，p< 0.001）和 SOTT（OR=1.523，95% CI 1.261 至 1.840，p<0.001）。ERM 的发生率与其他危险因素之间没有观察到统计学上显着的关联。术前 PVR 与 ERM 风险的相关性最强。ERM风险与SOTT、光凝能量和术前PVR等级呈正相关。结论接受SO填塞的RRD眼中ERM发生率为12.3%，而术前ERM诊断准确率较低。术前PVR、2型糖尿病、光凝能量和SOTT是ERM的主要危险因素。数据可根据合理要求提供。数据可能从第三方获得，并且不公开。与研究相关的所有数据都包含在文章中或作为补充信息上传。不适用。