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Improving Thermal Stability of Enzymatic Micromotors by a Temperature-Sensitive Smart Polymeric Shell
ChemNanoMat ( IF 2.6 ) Pub Date : 2022-02-18 , DOI: 10.1002/cnma.202100447
Shengnan Wang 1 , Dandan Xu 1 , Xiaoxia Liu 1 , Yong Wang 1 , Heng Ye 1 , Xing Ma 1, 2
Affiliation  

An enzymatic micromotor with enhanced thermal stability provided by a temperature-sensitive polymer shell is reported. The asymmetrical consumption of urea by urease is the driving force to the micromotors. Shell shrinking at elevated temperatures can effectively protect the protein chains from structure transformation and subunit dissociation, which are the main reasons for enzyme denaturation at high temperatures.

中文翻译:

通过温度敏感的智能聚合物外壳提高酶促微电机的热稳定性

报道了一种由温度敏感聚合物外壳提供的具有增强热稳定性的酶促微电机。尿素酶对尿素的不对称消耗是微电机的驱动力。高温缩壳可以有效保护蛋白质链不发生结构转变和亚基解离,这是酶在高温下变性的主要原因。
更新日期:2022-02-18
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