High-performance polymer membranes have attracted attention as excellent candidates for the fabrication of separation materials owing to their high versatility and ease of processability. Membranes can be prepared from polymers through solvent evaporation, phase inversion, coating, or interfacial polymerization. Organic solvent nanofiltration (OSN) processes require membranes with high solvent resistance, excellent thermal and chemical stability, and high separation performance. Polymer membranes have shown great potential in OSN for separating valuable pharmaceutical compounds, dyes, and other organic molecules within a molecular weight range of 100–2000 g mol⁻¹ in organic solvents. Polymers of intrinsic microporosity (PIMs) have been used to fabricate OSN membranes with outstanding thermal and chemical stability in addition to high intrinsic porosity. In this study, we discuss different design aspects that should be considered for achieving high performance in advanced PIM-based OSN membranes operating under harsh conditions.

高性能聚合物膜由于其高通用性和易于加工性而作为制备分离材料的优秀候选物而受到关注。可以通过溶剂蒸发、相转化、涂布或界面聚合从聚合物制备膜。有机溶剂纳滤 (OSN) 工艺需要具有高耐溶剂性、优异的热稳定性和化学稳定性以及高分离性能的膜。聚合物膜在 OSN 中显示出巨大的潜力，可用于分离分子量范围为 100-2000 g mol ^{-1的有价值的药物化合物、染料和其他有机分子}在有机溶剂中。除了高固有孔隙率外，固有微孔率聚合物 (PIM) 已被用于制造具有出色热稳定性和化学稳定性的 OSN 膜。在本研究中，我们讨论了在恶劣条件下运行的先进 PIM 基 OSN 膜实现高性能时应考虑的不同设计方面。