The tumor ecosystem evolves with dynamic interactions between cancer and normal cells, and nutrients have emerged as new regulators of cancer hallmarks. Lactate has climbed the rankings as a multifunctional molecule orchestrating many aspects of the disease onset and progression. Here, we patchwork and discuss the main recent findings conferred during the EMBO workshop titled ‘Lactate: Unconventional Roles of a Nutrient Along the Tumor Landscape.’

中文翻译：

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乳酸在肿瘤和免疫景观中的非常规作用

肿瘤生态系统随着癌症和正常细胞之间的动态相互作用而发展，营养物质已成为癌症标志的新调节剂。乳酸作为一种多功能分子在疾病发作和进展的许多方面的作用已经攀升。在这里，我们拼凑并讨论了在题为“乳酸：营养物质在肿瘤景观中的非常规作用”的 EMBO 研讨会期间获得的主要最新发现。