Bipolar disorder is a highly disruptive and debilitating problem. Mindfulness-based and mindfulness-informed interventions have exponentially emerged as third-generation therapies, applied to a wide spectrum of disorders, including bipolar disorder. However, the reviews and meta-analyses published to date are limited in their conclusions, as they are based on single-group pretest–posttest cohort designs and mostly focused on mindfulness-based interventions. The present review and meta-analysis try to address these limitations, including studies on informed mindfulness, controlled and single-group designs. It used a specific meta-analytical procedure that allows an imputation procedure in those designs lacking a comparison group, by means of separate omnibus tests for the experimental and control group. A total of 13 studies (N = 331) were selected. The results showed an absence of effects on depression (g = 0.21) and mania (g = −0.13), but significant moderate effect on anxiety (g = 0.53). In conclusion, both mindfulness interventions showed robust evidence on anxiety symptoms in pretest–posttest periods compared to control groups. Few studies and lack of evidence of follow-up periods were the main limitations found.

中文翻译：

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双相情感障碍中基于正念和正念的干预：基于贝克尔方法的荟萃分析

双相情感障碍是一个极具破坏性和使人衰弱的问题。基于正念和正念的干预措施已作为第三代疗法成倍出现，适用于包括双相情感障碍在内的广泛疾病。然而，迄今为止发表的评论和荟萃分析的结论有限，因为它们基于单组前测-后测队列设计，并且主要关注基于正念的干预措施。本综述和荟萃分析试图解决这些局限性，包括对知情正念、控制和单组设计的研究。它使用了一种特定的元分析程序，通过对实验组和对照组进行单独的综合测试，允许在缺乏对照组的设计中进行插补程序。共有 13 项研究 (N  = 331) 被选中。结果显示对抑郁症（g  = 0.21）和躁狂症（g = -0.13）没有影响，但对焦虑症（ g  = 0.53） 有显着的中度影响。总之，与对照组相比，两种正念干预都显示出在前测-后测期间焦虑症状的有力证据。很少有研究和缺乏随访期的证据是发现的主要局限性。