Several lifestyle factors have been linked to risk for heart failure (HF) and premature mortality. The aim of this study was to estimate the impact of a healthy lifestyle on life expectancy with and without HF among men and women from a general population. This study was performed among 6113 participants (mean age 65.8 ± 9.7 years; 58.9% women) from the Rotterdam Study, a large prospective population-based cohort study. A continuous lifestyle score was created based on five lifestyle factors: smoking status, alcohol consumption, diet quality, physical activity and weight status (assessed 1995–2008). The lifestyle score was categorized into three levels: unhealthy (reference), intermediate and healthy. Gompertz regression and multistate life tables were used to estimate the effects of lifestyle on life expectancy with and without HF in men and women separately at ages 45, 65 and 85 years (follow-up until 2016). During an average follow-up of 11.3 years, 699 incident HF events and 2146 deaths occurred. At the age of 45 years, men in the healthy lifestyle category had a 4.4 (95% CI: 4.1–4.7) years longer total life expectancy than men in the unhealthy lifestyle category, and a 4.8 (95% CI: 4.4–5.1) years longer life expectancy free of HF. Among women, the difference in total life-expectancy at the age of 45 years was 3.4 (95% CI: 3.2–3.5) years and was 3.4 (95% CI: 3.3–3.6) years longer for life expectancy without HF. This effect persisted also at older ages. An overall healthy lifestyle can have a positive impact on total life expectancy and life expectancy free of HF.

一些生活方式因素与心力衰竭 (HF) 和过早死亡的风险有关。本研究的目的是评估健康生活方式对普通人群中男性和女性的预期寿命的影响。这项研究是在来自鹿特丹研究的 6113 名参与者（平均年龄 65.8 ± 9.7 岁；58.9% 的女性）中进行的，该研究是一项大型前瞻性基于人群的队列研究。根据五个生活方式因素创建连续生活方式评分：吸烟状况、饮酒、饮食质量、身体活动和体重状况（1995-2008 年评估）。生活方式评分分为三个等级：不健康（参考）、中等和健康。使用 Gompertz 回归和多状态生命表来估计生活方式对 45、65 和 85 岁男性和女性的预期寿命的影响（随访至 2016 年）。在 11.3 年的平均随访期间，发生了 699 起 HF 事件和 2146 例死亡。在 45 岁时，健康生活方式类别中的男性的总预期寿命比不健康生活方式类别中的男性长 4.4 年（95% CI：4.1-4.7）和 4.8（95% CI：4.4-5.1）年无 HF 的预期寿命更长。在女性中，45 岁时总预期寿命的差异为 3.4（95% CI：3.2-3.5）年，而没有 HF 的预期寿命延长了 3.4（95% CI：3.3-3.6）年。这种影响在老年人中也持续存在。