Most cancer cases occur in low- and middle-income countries (LMICs). The sophisticated technical and human infrastructure needed for optimal diagnosis, treatment, and monitoring of cancers is difficult enough in affluent countries; it is especially challenging in LMICs. In Western, educated, industrial, rich, democratic countries, there is a growing emphasis on and success with precision medicine, whereby targeted therapy is directed at cancers based on the specific genetic lesions in the cancer. Can such precision approaches be delivered in LMICs? We offer some examples of novel partnerships and creative solutions that suggest that precision medicine may be possible in LMICs given heavy doses of will, creativity, and persistence and a little luck.

中文翻译：

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低收入和中等收入国家的精准医疗


大多数癌症病例发生在低收入和中等收入国家 (LMIC)。在富裕国家，癌症最佳诊断、治疗和监测所需的先进技术和人力基础设施已经够困难的了；这在中低收入国家尤其具有挑战性。在西方、受过教育的、工业化的、富裕的、民主的国家，人们越来越重视精准医疗并取得成功，即根据癌症中的特定遗传病变针对癌症进行靶向治疗。中低收入国家能否提供这种精确的方法？我们提供了一些新颖的合作伙伴关系和创造性解决方案的例子，这些例子表明，只要有大量的意志、创造力、毅力和一点运气，中低收入国家就有可能实现精准医疗。