Due to the increasing population of individuals with cardiovascular diseases and related comorbidities, there is an increasing need for development of synergistic therapeutics. Monocytes are implicated in a broad spectrum of diseases and can serve as a focal point for therapeutic targeting. This review discusses the role of monocytes in cardiovascular diseases and highlights trends in monocyte targets nanoparticles in three cardiovascular-related diseases: Diabetes, Atherosclerosis, and HIV. Finally, the review offers perspectives on how to develop nanoparticle monocyte targeting strategies that can be beneficial for treating co-morbidities.

中文翻译：

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单核细胞作为心血管疾病的聚合纳米颗粒治疗靶点

由于患有心血管疾病和相关合并症的人数不断增加，对开发协同疗法的需求日益增加。单核细胞与多种疾病有关，可以作为治疗靶向的焦点。这篇综述讨论了单核细胞在心血管疾病中的作用，并强调了单核细胞靶向纳米粒子在三种心血管相关疾病（糖尿病、动脉粥样硬化和艾滋病毒）中的趋势。最后，该综述提供了有关如何开发有利于治疗合并症的纳米颗粒单核细胞靶向策略的观点。