Hip dysplasia is a common cause of hip pain and a known risk factor for hip osteoarthritis (OA) and early total hip arthroplasty (THA). Unfortunately, little is known about the specific factors associated with an increased risk of OA. The purpose was (i) to report the overall rate of symptomatic hip OA and THA and (ii) to identify radiographic features and patient characteristics associated with the development of symptomatic hip OA. A geographic database was used to identify all patients aged 14–50 years old diagnosed with symptomatic hip dysplasia between 2000 and 2016. Kaplan–Meier analysis was used to determine the rate of symptomatic hip OA, defined as a Tönnis grade of ≥1 on hip radiograph. Univariate and multivariate proportional hazard regression models were performed to determine risk factors for OA. One hundred and fifty-nine hips (144 patients) with hip dysplasia (52 F:107 M) out of 1893 patients with hip pain were included. Of these, 45 (28%) had severe hip dysplasia with a lateral center-edge angle ≤18°. Mean age at time of presentation was 26.1 (±10.1) years. Mean follow-up time was 8.2 (±5) years. The rate of OA was 20%. THA was performed in 11% of patients. Body mass index >29 (P = 0.03) and increased age (P < 0.01) were risk factors for OA. Patients with symptomatic hip dysplasia are at significant risk of developing hip OA. Body mass index >29 and age ≥35 years at the time of presentation with hip pain were risk factors for hip OA.

中文翻译：

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未经手术干预的髋关节发育不良患者长期髋关节骨关节炎的危险因素

髋关节发育不良是髋关节疼痛的常见原因，也是髋关节骨关节炎 (OA) 和早期全髋关节置换术 (THA) 的已知危险因素。不幸的是，对于与 OA 风险增加相关的具体因素知之甚少。目的是 (i) 报告症状性髋 OA 和 THA 的总体发生率，以及 (ii) 确定与症状性髋 OA 发展相关的影像学特征和患者特征。地理数据库用于识别 2000 年至 2016 年期间诊断为症状性髋关节发育不良的所有 14-50 岁患者。Kaplan-Meier 分析用于确定症状性髋关节 OA 的发生率，定义为髋关节 Tönnis 分级≥1射线照相。进行单变量和多变量比例风险回归模型以确定 OA 的危险因素。在 1893 名髋关节疼痛患者中，有 159 名髋关节（144 名患者）患有髋关节发育不良 (52 F:107 M)。其中，45 人（28%）患有严重的髋关节发育不良，侧向中心边缘角≤18°。就诊时的平均年龄为 26.1 (±10.1) 岁。平均随访时间为 8.2 (±5) 年。OA率为20%。11% 的患者进行了 THA。体重指数 > 29 (P = 0.03) 和年龄增加 (P < 0.01) 是 OA 的危险因素。有症状性髋关节发育不良的患者发生髋关节 OA 的风险很大。体重指数＞29 和出现髋部疼痛时年龄≥35 岁是髋部 OA 的危险因素。就诊时的平均年龄为 26.1 (±10.1) 岁。平均随访时间为 8.2 (±5) 年。OA率为20%。11% 的患者进行了 THA。体重指数 > 29 (P = 0.03) 和年龄增加 (P < 0.01) 是 OA 的危险因素。有症状性髋关节发育不良的患者发生髋关节 OA 的风险很大。体重指数＞29 和出现髋部疼痛时年龄≥35 岁是髋部 OA 的危险因素。就诊时的平均年龄为 26.1 (±10.1) 岁。平均随访时间为 8.2 (±5) 年。OA率为20%。11% 的患者进行了 THA。体重指数 > 29 (P = 0.03) 和年龄增加 (P < 0.01) 是 OA 的危险因素。有症状性髋关节发育不良的患者发生髋关节 OA 的风险很大。体重指数＞29 和出现髋部疼痛时年龄≥35 岁是髋部 OA 的危险因素。