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Association Between Dementia Development and COVID-19 among Individuals Who Tested Negative for COVID-19 in South Korea: A Nationwide Cohort Study
American Journal of Alzheimer's Disease and other Dementias ( IF 2.7 ) Pub Date : 2022-01-20 , DOI: 10.1177/15333175211072387
Namwoo Kim 1, 2 , Sungtaek Son 3 , Saemina Kim 3 , Jieun Lee 4 , Yong Min Ahn 1, 5 , Dong Keon Yon 6 , Bong-Jin Hahm 1, 5
Affiliation  

We aim to assess whether the number of newly diagnosed dementia increases and whether comorbid psychiatric symptoms of patients with dementia worsen, in people who were tested for COVID-19. We used electronic medical records from a nationwide cohort consisting of people who tested positive (positive group), tested negative (negative group), and those who did not receive the test (control group) for COVID-19. For people with neither a history of dementia nor mild cognitive disorder (MCI), the negative group was more likely to develop dementia than the control group, and less likely to develop MCI than the positive group. For people who already had dementia, the negative group was more likely to develop comorbid psychiatric disorders than the control group, but less likely than the positive group. These findings suggest the necessity of managing mental health not only for patients with COVID-19 but also for people who tested negative for COVID-19.



中文翻译:

韩国 COVID-19 检测呈阴性的个体痴呆症发展与 COVID-19 之间的关联:一项全国性队列研究

我们旨在评估接受 COVID-19 检测的人群中新诊断的痴呆症的数量是否增加,以及痴呆症患者的合并精神症状是否恶化。我们使用了一个全国性队列的电子病历,该队列由检测呈阳性(阳性组)、检测呈阴性(阴性组)和未接受 COVID-19 检测(对照组)的人组成。对于既没有痴呆病史也没有轻度认知障碍 (MCI) 的人,阴性组比对照组更容易患痴呆症,并且比阳性组更不可能发生 MCI。对于已经患有痴呆症的人来说,阴性组比对照组更容易出现合并精神疾病,但比阳性组更不可能。

更新日期:2022-01-20
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