Purpose: The authors examined associations between preschoolers’ daily glycemic variability, parents’ report of hypoglycemia fear, and preschoolers’ daily moderate to vigorous physical activity (MVPA) and sedentary behavior (SB) in 25 families of preschoolers with type 1 diabetes. Methods: Parents completed a valid measure of hypoglycemia fear, and their child wore an accelerometer for up to 7 days. Parents provided glucose data from their child’s devices. The authors used multiple regression and multilevel modeling to analyze their data. Results: Preschoolers (mean age 4.2 [1.7] y; 50% boys) engaged in a mean of 154.5 (59.6) and 339.2 (85.1) minutes of MVPA and SB per day, respectively, and parents reported relatively low levels of hypoglycemia worry and avoidance behaviors. Preschoolers’ SB (r = .19, P = .02) and MVPA (r = −.20, P = .01) levels were significantly correlated with parental hypoglycemia worry scores but not with parents’ hypoglycemia behavior scores (P = .15 and P = .92, respectively). While multilevel models did not show an association between MVPA and preschoolers’ glycemic variability, preschoolers who engaged in more daily SB experienced higher glycemic variability (P = .04). Conclusions: Research exploring MVPA, SB, and parental hypoglycemia fear in preschoolers with type 1 diabetes could have important clinical implications because it may reveal modifiable treatment targets that can impact preschoolers’ health and activity patterns.

目的：作者在 25 个患有 1 型糖尿病的学龄前儿童家庭中研究了学龄前儿童每日血糖变异性、家长对低血糖恐惧的报告以及学龄前儿童每日中等至剧烈体力活动 (MVPA) 和久坐行为 (SB) 之间的关联。方法：父母完成了对低血糖恐惧的有效测量，并且他们的孩子佩戴加速度计长达 7 天。家长通过孩子的设备提供血糖数据。作者使用多元回归和多级建模来分析他们的数据。结果：学龄前儿童（平均年龄 4.2 [1.7] 岁；50% 是男孩）每天平均分别进行 154.5 (59.6) 分钟和 339.2 (85.1) 分钟的 MVPA 和 SB，家长报告的低血糖担忧程度相对较低，回避行为。学龄前儿童的 SB ( r = .19, P = .02) 和 MVPA ( r = −.20, P = .01) 水平与父母低血糖担忧评分显着相关，但与父母低血糖行为评分无关 ( P = .15和P = .92，分别）。虽然多水平模型并未显示 MVPA 与学龄前儿童的血糖变异性之间存在关联，但每天进行更多 SB 的学龄前儿童的血糖变异性较高 ( P = .04)。结论：探索 1 型糖尿病学龄前儿童的 MVPA、SB 和父母低血糖恐惧的研究可能具有重要的临床意义，因为它可能揭示可影响学龄前儿童健康和活动模式的可修改治疗目标。