Abstract

Carbon nanofibers are promising green materials for sustainable technology within a wide range of applications including environment, energy, health and high-technology. Accordingly, drug adsorption is an important subject in connection with its environmental and pharmaceutical applications. This study aims to investigate the adsorption performance of carbon nanofibers in batch and fixed bed column processes. Carbon nanofibers were used as adsorbent to remove triflupromazine hdyrochloride from aqueous solutions. Adsorption kinetics were studied using Lagergren first order and Pseudo second order models. Intraparticle diffusion graph was plotted using kinetic data and showed that intraparticle diffusion is the single step controlling the adsorption rate. Experimental equilibrium data was modeled by using Langmuir and Freundlich equations and has a better fit to the Langmuir model. Triflupromazine adsorption on carbon nanofibers was found to be H-type according to Giles classification. The effect of temperature and the effect of pH on adsorption were studied to determine optimum adsorption conditions. Adsorption capacity of carbon nanofibers was decreased with increasing temperature due to the exothermic and physical nature of the process. Thermodynamic parameters confirmed the exothermic nature of the adsorption. Results showed the effective adsorption of drug molecules by carbon nanofibers. Maximum adsorption capacity was calculated as 165.41 mg/g at pH 9 using Langmuir equation. Modeling of the fixed bed column data was done by using Thomas model and Yoon–Nelson model. Results showed the important effect of the operating conditions on the removal performance of carbon nanofibers. Removal capacity was increased with an increase in the flow rate and the increase in the fixed bed length.

摘要

碳纳米纤维是有前途的绿色材料，可用于环境、能源、健康和高科技等广泛应用中的可持续技术。因此，药物吸附是与其环境和药物应用相关的重要课题。本研究旨在研究碳纳米纤维在间歇和固定床柱工艺中的吸附性能。碳纳米纤维用作吸附剂以从水溶液中去除盐酸三氟丙嗪。使用 Lagergren 一阶和伪二阶模型研究吸附动力学。使用动力学数据绘制颗粒内扩散图并显示颗粒内扩散是控制吸附速率的单个步骤。实验平衡数据通过使用 Langmuir 和 Freundlich 方程建模，并更好地拟合 Langmuir 模型。根据Giles分类发现三氟丙嗪在碳纳米纤维上的吸附是H型的。研究了温度和pH对吸附的影响，以确定最佳吸附条件。由于该过程的放热和物理性质，碳纳米纤维的吸附能力随着温度的升高而降低。热力学参数证实了吸附的放热性质。结果表明碳纳米纤维对药物分子的有效吸附。使用 Langmuir 方程在 pH 9 下计算出最大吸附容量为 165.41 mg/g。使用 Thomas 模型和 Yoon-Nelson 模型对固定床柱数据进行建模。结果表明，操作条件对碳纳米纤维的去除性能有重要影响。去除能力随着流速的增加和固定床长度的增加而增加。