当前位置：
X-MOL 学术
›
Br. J. Surg.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Microsatellite instability in young patients with rectal cancer: molecular findings and treatment response
British Journal of Surgery ( IF 8.6 ) Pub Date : 2021-11-25 , DOI: 10.1093/bjs/znab437 , Alexandra M Zaborowski , Ahmed Abdile , Michel Adamina , Felix Aigner , Laura d'Allens , Caterina Allmer , Andrea Álvarez , Rocio Anula , Mihailo Andric , Sam Atallah , Simon Bach , Miklosh Bala , Marie Barussaud , Augustinas Bausys , Andrew Beggs , Felipe Bellolio , Melissa-Rose Bennett , Anton Berdinskikh , Vicki Bevan , Sebastiano Biondo , Gabriele Bislenghi , Marc Bludau , Nelleke Brouwer , Carl Brown , Christiane Bruns , Daniel D Buchanan , Pamela Buchwald , Jacobus W A Burger , Nikita Burlov , Michela Campanelli , Maylis Capdepont , Michele Carvello , Hwee-Hoon Chew , Dimitri Christoforidis , David Clark , Marta Climent , Rowan Collinson , Kyle G Cologne , Tomas Contreras , Roland Croner , Ian R Daniels , Giovanni Dapri , Justin Davies , Paolo Delrio , Quentin Denost , Michael Deutsch , Andre Dias , André D'Hoore , Evgeniy Drozdov , Daniel Duek , Malcolm Dunlop , Adam Dziki , Aleksandra Edmundson , Sergey Efetov , Alaa El-Hussuna , Brodie Elliot , Sameh Emile , Eloy Espin , Martyn Evans , Seraina Faes , Omar Faiz , Nuno Figueiredo , Fergal Fleming , Caterina Foppa , George Fowler , Matteo Frasson , Tim Forgan , Frank Frizelle , Shamil Gadaev , Jose Gellona , Tamara Glyn , Barisic Goran , Emma Greenwood , Marianne G Guren , Stephanie Guillon , Ida Gutlic , Dieter Hahnloser , Heather Hampel , Ann Hanly , Hirotoshi Hasegawa , Lene Hjerrild Iversen , Andrew Hill , James Hill , Jiri Hoch , Roel Hompes , Luis Hurtado , Fabiano Iaquinandi , Ugne Imbrasaite , Rumana Islam , Mehrenah D Jafari , Andrea Jiménez Salido , Marta Jiménez Toscano , Yukihide Kanemitsu , Aleksei Karachun , Ahmer A Karimuddin , Deborah S Keller , Justin Kelly , Rory Kennelly , Gleb Khrykov , Peter Kocian , Cherry Koh , Neils Kok , Katrina A Knight , Joep Knol , Christos Kontovounisios , Hartwig Korner , Zoran Krivokapic , Irmgard Kronberger , Hidde Maarten Kroon , Marius Kryzauskas , Said Kural , Miranda Kusters , Zaher Lakkis , Timur Lankov , David Larson , György Lázár , Kai-Yin Lee , Suk Hwan Lee , Jérémie H Lefèvre , Anna Lepisto , Christopher Lieu , Lynette Loi , Craig Lynch , Helene Maillou-Martinaud , Annalisa Maroli , Sean Martin , Anna Martling , Klaus E Matzel , Julio Mayol , Frank McDermott , Guillaume Meurette , Monica Millan , Martin Mitteregger , Andrei Moiseenko , John R T Monson , Stefan Morarasu , Konosuke Moritani , Gabriela Möslein , Martino Munini , Caio Nahas , Sergio Nahas , Ionut Negoi , Anastasia Novikova , Misael Ocares , Koji Okabayashi , Alexandra Olkina , Luis Oñate-Ocaña , Jaime Otero , Cihan Ozen , Ugo Pace , Guilherme Pagin São Julião , Lidiia Panaiotti , Yves Panis , Demetris Papamichael , Swati Patel , Juan Carlos Patrón Uriburu , Sze-Lin Peng , Miguel Pera , Rodrigo O Perez , Alexei Petrov , Frank Pfeffer , Terry P Phang , Tomas Poskus , Heather Pringle , David Proud , Ivana Raguz , Nuno Rama , Shahnawaz Rasheed , Manoj J Raval , Daniela Rega , Christoph Reissfelder , Juan Carlos Reyes Meneses , Frederic Ris , Stefan Riss , Homero Rodriguez-Zentner , Campbell S Roxburgh , Avanish Saklani , Tarik Sammour , Deborah Saraste , Martin Schneider , Ryo Seishima , Aleksander Sekulic , Toni Seppala , Kieran Sheahan , Alexandra Shlomina , Guiseppe Sigismondo , Tongplaew Singnomklao , Leandro Siragusa , Neil Smart , Alejandro Solis-Peña , Antonino Spinelli , Roxane D Staiger , Michael J Stamos , Scott Steele , Ker-Kan Tan , Pieter J Tanis , Paris Tekkis , Biniam Teklay , Sabrina Tengku , Petr Tsarkov , Matthias Turina , Alexis Ulrich , Bruna B Vailati , Meike van Harten , Cornelis Verhoef , Satish Warrier , Steven Wexner , Hans de Wilt , Benjamin A Weinberg , Cameron Wells , Albert Wolthuis , Evangelos Xynos , Nancy You , Alexander Zakharenko , Justino Zeballos , Jonathan Zhou , Des C Winter
British Journal of Surgery ( IF 8.6 ) Pub Date : 2021-11-25 , DOI: 10.1093/bjs/znab437 , Alexandra M Zaborowski , Ahmed Abdile , Michel Adamina , Felix Aigner , Laura d'Allens , Caterina Allmer , Andrea Álvarez , Rocio Anula , Mihailo Andric , Sam Atallah , Simon Bach , Miklosh Bala , Marie Barussaud , Augustinas Bausys , Andrew Beggs , Felipe Bellolio , Melissa-Rose Bennett , Anton Berdinskikh , Vicki Bevan , Sebastiano Biondo , Gabriele Bislenghi , Marc Bludau , Nelleke Brouwer , Carl Brown , Christiane Bruns , Daniel D Buchanan , Pamela Buchwald , Jacobus W A Burger , Nikita Burlov , Michela Campanelli , Maylis Capdepont , Michele Carvello , Hwee-Hoon Chew , Dimitri Christoforidis , David Clark , Marta Climent , Rowan Collinson , Kyle G Cologne , Tomas Contreras , Roland Croner , Ian R Daniels , Giovanni Dapri , Justin Davies , Paolo Delrio , Quentin Denost , Michael Deutsch , Andre Dias , André D'Hoore , Evgeniy Drozdov , Daniel Duek , Malcolm Dunlop , Adam Dziki , Aleksandra Edmundson , Sergey Efetov , Alaa El-Hussuna , Brodie Elliot , Sameh Emile , Eloy Espin , Martyn Evans , Seraina Faes , Omar Faiz , Nuno Figueiredo , Fergal Fleming , Caterina Foppa , George Fowler , Matteo Frasson , Tim Forgan , Frank Frizelle , Shamil Gadaev , Jose Gellona , Tamara Glyn , Barisic Goran , Emma Greenwood , Marianne G Guren , Stephanie Guillon , Ida Gutlic , Dieter Hahnloser , Heather Hampel , Ann Hanly , Hirotoshi Hasegawa , Lene Hjerrild Iversen , Andrew Hill , James Hill , Jiri Hoch , Roel Hompes , Luis Hurtado , Fabiano Iaquinandi , Ugne Imbrasaite , Rumana Islam , Mehrenah D Jafari , Andrea Jiménez Salido , Marta Jiménez Toscano , Yukihide Kanemitsu , Aleksei Karachun , Ahmer A Karimuddin , Deborah S Keller , Justin Kelly , Rory Kennelly , Gleb Khrykov , Peter Kocian , Cherry Koh , Neils Kok , Katrina A Knight , Joep Knol , Christos Kontovounisios , Hartwig Korner , Zoran Krivokapic , Irmgard Kronberger , Hidde Maarten Kroon , Marius Kryzauskas , Said Kural , Miranda Kusters , Zaher Lakkis , Timur Lankov , David Larson , György Lázár , Kai-Yin Lee , Suk Hwan Lee , Jérémie H Lefèvre , Anna Lepisto , Christopher Lieu , Lynette Loi , Craig Lynch , Helene Maillou-Martinaud , Annalisa Maroli , Sean Martin , Anna Martling , Klaus E Matzel , Julio Mayol , Frank McDermott , Guillaume Meurette , Monica Millan , Martin Mitteregger , Andrei Moiseenko , John R T Monson , Stefan Morarasu , Konosuke Moritani , Gabriela Möslein , Martino Munini , Caio Nahas , Sergio Nahas , Ionut Negoi , Anastasia Novikova , Misael Ocares , Koji Okabayashi , Alexandra Olkina , Luis Oñate-Ocaña , Jaime Otero , Cihan Ozen , Ugo Pace , Guilherme Pagin São Julião , Lidiia Panaiotti , Yves Panis , Demetris Papamichael , Swati Patel , Juan Carlos Patrón Uriburu , Sze-Lin Peng , Miguel Pera , Rodrigo O Perez , Alexei Petrov , Frank Pfeffer , Terry P Phang , Tomas Poskus , Heather Pringle , David Proud , Ivana Raguz , Nuno Rama , Shahnawaz Rasheed , Manoj J Raval , Daniela Rega , Christoph Reissfelder , Juan Carlos Reyes Meneses , Frederic Ris , Stefan Riss , Homero Rodriguez-Zentner , Campbell S Roxburgh , Avanish Saklani , Tarik Sammour , Deborah Saraste , Martin Schneider , Ryo Seishima , Aleksander Sekulic , Toni Seppala , Kieran Sheahan , Alexandra Shlomina , Guiseppe Sigismondo , Tongplaew Singnomklao , Leandro Siragusa , Neil Smart , Alejandro Solis-Peña , Antonino Spinelli , Roxane D Staiger , Michael J Stamos , Scott Steele , Ker-Kan Tan , Pieter J Tanis , Paris Tekkis , Biniam Teklay , Sabrina Tengku , Petr Tsarkov , Matthias Turina , Alexis Ulrich , Bruna B Vailati , Meike van Harten , Cornelis Verhoef , Satish Warrier , Steven Wexner , Hans de Wilt , Benjamin A Weinberg , Cameron Wells , Albert Wolthuis , Evangelos Xynos , Nancy You , Alexander Zakharenko , Justino Zeballos , Jonathan Zhou , Des C Winter
In this study of 400 patients with early-onset rectal cancer, 12.5 per cent demonstrated microsatellite instability (MSI). MSI was associated with a reduced likelihood of nodal positivity, an increased rate of pathological complete response, and improved disease-specific survival.
中文翻译：
年轻直肠癌患者的微卫星不稳定性：分子发现和治疗反应
在这项针对 400 名早发直肠癌患者的研究中，12.5% 的患者表现出微卫星不稳定性 (MSI)。 MSI 与淋巴结阳性可能性降低、病理完全缓解率增加以及疾病特异性生存率提高相关。
更新日期：2021-11-25
中文翻译：
年轻直肠癌患者的微卫星不稳定性：分子发现和治疗反应
在这项针对 400 名早发直肠癌患者的研究中，12.5% 的患者表现出微卫星不稳定性 (MSI)。 MSI 与淋巴结阳性可能性降低、病理完全缓解率增加以及疾病特异性生存率提高相关。
京公网安备 11010802027423号