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Buprenorphine: a treatment and cause of opioid-induced respiratory depression
British Journal of Anaesthesia ( IF 9.1 ) Pub Date : 2022-01-05 , DOI: 10.1016/j.bja.2021.12.001
Albert Dahan 1 , Maarten van Lemmen 1 , Simone Jansen 1 , Pieter Simons 1 , Rutger van der Schrier 1
Affiliation  

Buprenorphine is a partial agonist at the mu opioid receptor. Due to its relatively low maximum effect on respiratory depression it is considered by some to be a safe opioid. But it can produce serious respiratory depression, particularly when combined with sedatives such as benzodiazepines.



中文翻译:

丁丙诺啡:阿片类药物引起的呼吸抑制的治疗方法和原因

丁丙诺啡是μ阿片受体的部分激动剂。由于其对呼吸抑制的最大影响相对较低,因此一些人认为它是一种安全的阿片类药物。但它会产生严重的呼吸抑制,尤其是与苯二氮卓类药物等镇静剂合用时。

更新日期:2022-01-05
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