Magnesium (Mg) and its alloys are promising candidates for use in bone tissue engineering due to their good biocompatibility and mechanical stability. Nonetheless, the fast biodegradation of Mg in physiological media inhibits its use as a bone graft material. Aiming to improve its corrosion resistance, a dicalcium phosphate dihydrate (DCPD, brushite) coating was initially deposited on the hot-rolled Mg substrates by immersion in a phosphating bath at room temperature for 24 h. Polyvinyl alcohol-bioactive glass (PVA-BG) composite coatings were then deposited by dip-coating on these materials. The samples were tested for structure, corrosion behavior, and biocompatibility. The composite coatings significantly increased the corrosion protection of Mg and also accelerated the formation of HAp on its surface when soaked in a simulated body fluid (SBF). Flow cytometry assays revealed that the composites prepared had high cell viability (over 90%) when immortalized human embryonic kidney cells were tested. The coating method investigated in this work is simple, environmentally friendly, safe, and easily scalable. It is the first time that this approach is reported in the literature, which highlights its novelty.

镁 (Mg) 及其合金具有良好的生物相容性和机械稳定性，是用于骨组织工程的有希望的候选材料。尽管如此，Mg 在生理介质中的快速生物降解抑制了其作为骨移植材料的用途。为了提高其耐腐蚀性，首先通过在室温下浸入磷化浴中 24 小时在热轧 Mg 基材上沉积二水合磷酸二钙（DCPD，透钙磷石）涂层。然后通过浸涂在这些材料上沉积聚乙烯醇-生物活性玻璃 (PVA-BG)复合涂层。对样品的结构、腐蚀行为和生物相容性进行了测试。复合涂层显着增加了镁的腐蚀保护，也加速了HAp浸泡在模拟体液 (SBF) 中时在其表面上。流式细胞仪分析表明，当测试永生化人胚胎肾细胞时，制备的复合材料具有高细胞活力（超过 90%）。本工作研究的涂层方法简单、环保、安全且易于扩展。这是第一次在文献中报道这种方法，这突出了它的新颖性。