The present critical review was conducted to evaluate the clinimetric properties of the Charlson Comorbidity Index (CCI), an assessment tool designed specifically to predict long-term mortality, with regard to its reliability, concurrent validity, sensitivity, incremental and predictive validity. The original version of the CCI has been adapted for use with different sources of data, ICD-9 and ICD-10 codes. The inter-rater reliability of the CCI was found to be excellent, with extremely high agreement between self-report and medical charts. The CCI has also been shown either to have concurrent validity with a number of other prognostic scales or to result in concordant predictions. Importantly, the clinimetric sensitivity of the CCI has been demonstrated in a variety of medical conditions, with stepwise increases in the CCI associated with stepwise increases in mortality. The CCI is also characterized by the clinimetric property of incremental validity, whereby adding the CCI to other measures increases the overall predictive accuracy. It has been shown to predict long-term mortality in different clinical populations, including medical, surgical, intensive care unit (ICU), trauma, and cancer patients. It may also predict in-hospital mortality, although in some instances, such as ICU or trauma patients, the CCI did not perform as well as other instruments designed specifically for that purpose. The CCI thus appears to be clinically useful not only to provide a valid assessment of the patient’s unique clinical situation, but also to demarcate major diagnostic and prognostic differences among subgroups of patients sharing the same medical diagnosis.
Psychother Psychosom

中文翻译：

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查尔森合并症指数：临床特性的批判性审查

本次严格审查旨在评估 Charlson 合并症指数 (CCI) 的临床特性，该指数是一种专门用于预测长期死亡率的评估工具，包括其可靠性、同时效度、敏感性、增量效度和预测效度。CCI 的原始版本已针对不同的数据源、ICD-9 和 ICD-10 代码进行了调整。发现 CCI 的评估者间可靠性非常好，自我报告和医疗图表之间的一致性非常高。CCI 也被证明与许多其他预后量表具有同时有效性或导致一致的预测。重要的是，CCI 的临床敏感性已在各种医疗条件下得到证明，CCI 的逐步增加与死亡率的逐步增加有关。CCI 的特征还在于增量有效性的临床特性，因此将 CCI 添加到其他测量中可以提高整体预测准确性。它已被证明可以预测不同临床人群的长期死亡率，包括内科、外科、重症监护室 (ICU)、创伤和癌症患者。它还可以预测住院死亡率，尽管在某些情况下，例如 ICU 或创伤患者，CCI 的性能不如专门为此目的设计的其他仪器。因此，CCI 似乎在临床上有用，不仅可以提供对患者独特临床情况的有效评估，
心理治疗师